Mapping of Blood Group and Phenotypes Rhesus and Kell to Sickle Cell Desease Patients in Transfusion Program at the National Blood Transfusion Center (NBTC) of Abidjan Côte d’ivoire

The objective of this study is to establish the mapping of blood group and phenotype Rhesus and Kell and compare it to the population of blood donors. Methodology: It is a prospective study performed in transfusion therapy unit (UTT) of the national blood transfusion center (NBTC) of Abidjan on sickle cell desease patients multitransfused between February and October 2013. The blood group ABO and phenotype Rhesus and Kell of the patients was performed by the gel agglutination technique. The statistical analysis was performed using SPSS 15.0 software. Results: Among the 145 patients followed by the UTT, males predominated with (sex ratio 1.27). The median age was 14 years. Homozygous sickle cell disease (SS) was more frequent (57.25%). The blood group O was more represented (54.6%). Ag D was found in 96%. The Ag C (16.5%) and Ag E (14.5%) have lower frequencies than those founded in the population of blood donors (Ag C 21.6% and Ag E 22.2%). The most phenotype rhesus and kell frequently encountered to the patients was Cc+ Ee+ K(49.7%). These frequencies are lower than those of the blood donors population. Conclusion: Blood group O is the most common to our patients. The Ag D is the most found. The phenotype Rhesus and kell Cc + D + EeKpredominates with but remains below the frequencies reported among blood donors. This proves that there are risks of alloimmunization to these patients; hence the necessity to transfuse according to the protocol phenotyped and compatibility.